منابع مشابه
Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers
BACKGROUND The aim of this study was to compare the pharmacokinetic properties of sodium ibuprofen and ibuprofen acid incorporating poloxamer with standard ibuprofen acid tablets. METHODS Twenty-two healthy volunteers were enrolled into this randomised, single-dose, 3-way crossover, open-label, single-centre, pharmacokinetic study. After 14 hours' fasting, participants received a single dose ...
متن کاملHydrolysis of ibuprofen nitrile and ibuprofen amide and deracemisation of ibuprofen using Nocardia corallina B-276.
A novel application of whole cells of Nocardia corallina B-276 for the deracemisation of ibuprofen is reported. This microorganism successfully hydrolysed ibuprofen nitrile to ibuprofen amide, and ibuprofen amide to ibuprofen, using a suspension of cells in a potassium phosphate buffer solution (0.1 M, pH = 7.0). These results can be explained by the presence of NHase and amidase enzymes, but t...
متن کاملDetermination of Solubility Parameters of Ibuprofen and Ibuprofen Lysinate.
In recent years there has been a growing interest in formulating solid dispersions, which purposes mainly include solubility enhancement, sustained drug release and taste masking. The most notable problem by these dispersions is drug-carrier (in)solubility. Here we focus on solubility parameters as a tool for predicting the solubility of a drug in certain carriers. Solubility parameters were de...
متن کاملIbuprofen-Induced Hemolytic Anemia
Drug-induced immune hemolytic anemia is a rare condition with an incidence of 1 per million of the population. We report the case of a 36-year-old female who presented to the emergency department complaining of shortness of breath and dark colored urine. Physical examination was significant for pale mucous membranes. The patient reported using ibuprofen for a few days prior to presentation. Com...
متن کاملAcetaminophen and Ibuprofen overdosage.
An Update of N-acetylcysteine Treatment for Acute Acetaminophen Toxicity in Children. Marzullo L. Curr Opin Pediatr. 2005;17(2):239–245 Acetaminophen Toxicity in Children. American Academy of Pediatrics. Committee on Drugs. Pediatrics. 2001; 108(4):1020–1024 Clinical Report—Fever and Antipyretic Use in Children. Section on Clinical Pharmacology and Therapeutics; Committee on Drugs, Sullivan JE,...
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ژورنال
عنوان ژورنال: Reactions Weekly
سال: 2021
ISSN: ['1179-2051', '0114-9954']
DOI: https://doi.org/10.1007/s40278-021-95098-1